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Abuse and Overdose Percocet is undoubtedly an opioid painkiller, one of the most usually abused classes of prescription drugs. Abuse should not be bewildered with dependence. With Percocet abuse, drug use is compulsive and infrequently non-professional medical.After halting a CYP3A4 inhibitor, as the effects on the inhibitor decrease, the oxycodone